Keragel® has demonstrated faster epithelialization rates and more robust skin after healing in numerous clinical studies. In vitro studies have shown that Replicine™ Functional Keratin® increases the rates of proliferation and migration of keratinocyte cells (which play a key role in epithelialization) and that the migrating keratinocytes express increased levels of collagen 4 and collagen 7 which are critical for basal membrane integrity.